- Campral (acamprosate calcium) is a medication approved for the treatment of alcohol dependence or alcoholism in the United States -- approved by the Food and Drug Administration in July 2004 -- but it has been used widely in Europe for many years. More than 1.5 million people have been treated worldwide with Campral
How Does Campral Work?It is not completely understood exactly how Campral works in the brain to help people maintain
alcohol abstinence, but it is believed to restore a chemical balance in the brain that is disrupted by long-term or chronic alcohol abuse. In other words, it helps the brain begin working normally again.
While
Antabuse works by making someone sick if they drink alcohol and
Naltrexone blocks the "high" people get when drinking, Campral reduces the physical distress and emotional discomfort people usually experience when they quit drinking. According to Forest Laboratories, the distributor the drug in the U.S., Campral reduces sweating, anxiety and sleep disturbances that many experience during the early stages of alcohol abstinence.
How Is Campral Taken?Campral is prescribed in 333mg time-release tablets that are usually taken three times a day. For some patients, such as those with kidney disease, the standard dose may be adjusted by a physician. Because Campral tablets are time-release, they should be swallowed whole and never crushed, cut or chewed.
Because the side effects of Campral are few and mild and because Campral is not addictive, it is usually prescribed for up to 12 months after ceasing alcohol consumption.
What Are the Side Effects?Campral was "generally well-tolerated and side effects are usually mild and temporary. They include: Diarrhea,
Dizziness, Gas,Dry mouth,
Headache,
Insomnia, Itching, Joint or muscle pain, Loss of appetite,
Vomiting, Sweating, Anxiety or nervousness, Burning, pricking or tingling in arms, legs, hands, or feet,
DepressionWhat Campral Does Not Do
Campral does not help someone quit drinking; it does not control cravings. It helps better tolerate
withdrawal symptoms experienced while going through early detoxification from alcohol and drugs. Campral has been shown to reduce sleep disturbances, anxiety and mood swings
How Effective Is Campral?As with all other medications approved
for the treatment of alcohol dependence, Campral is most effective as a part of an overall program of recovery including therapy, counseling and/or support group participation.